In 1947, returning to the UK with two young children to support, Margaret Durrell starts a boarding house in Bournemouth. But any hopes of respectability are dashed as the tenants reveal themselves to be a host of eccentrics from a painter of nudes to a pair of glamorous young nurses whose late-night shifts combined with an ever-revolving roster of gentleman callers leading to a neighbourhood rumour that Margo is running a brothel. Margo's own two sons, Gerry and Nicholas, prove to be every bit as mischievous as their famous Uncle Gerald - and he himself returns periodically with weird and wonderful animals, from marmosets to monkeys, that are quite unsuitable for life in a Bournemouth garden.