In the fantastic Hope County of Montana, the preacher Joseph Seed declares himself to be the chosen one of God and creates a cult, called Eden's Gate, under the pretense of saving the residents of the area from the end of the world.

Take on the role in a bloody revolution against Pagan Min, the dictator of Kyrat. It is considered one of the most spectacular landscapes in the world, but it is located in a region of the Himalayas where a maniac has declared himself king and imposed his paranoid regime - and you must fight for your survival.